113 Skewing of T Helper axis towards Th1 and Th17 cells in sarcoid arthritis compared to non-articular sarcoidosis

Background: 10-15% of sarcoid patients are associated with arthropathy. Chronic arthritis is less common around 1%. Data on articular manifestations of the disease from India is sparse. We aimed to study the clinical manifestations of sarcoid arthritis patients from India. Methods: Case records of patients presenting to ten rheumatology centres from 2005 to 2017 with sarcoidosis were retrospectively reviewed. Joint involvement was assessed clinically, classified as acute or chronic depending on duration of symptoms lesser or greater than six months respectively.

Results: A total of 123 patients with sarcoid arthritis were reviewed. Table 1 sums up the mode of presentation. 58 patients were classified as Lofgren syndrome. Pattern of joint involvement revealed ankle as most commonly affected in both the groups. Wrist, MCP, MTP and PIP involvement was significantly more common in chronic sarcoid (table 1 …

113 Skewing of T Helper axis towards Th1 and Th17 cells in sarcoid arthritis compared to non-articular sarcoidosis

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